LIS365: Advanced Cloud Laboratory Information System (LIS)
State-of-the-art diagnostic technology engineered to meet the unique workflow requirements of clinical, medical, and toxicology laboratories. Automate specimen accessioning, bidirectional instrument interfacing, real-time result delivery, and insurance billing in an integrated single-window solution.
Unify Diagnostic Workflows with Zero Manual Transcriptions
Modern clinical laboratories, reference facilities, and toxicology centers must balance surging specimen volumes against acute staffing shortages and tightening reimbursement schedules.
LIS365 bridges this gap by replacing disconnected spreadsheets and manual analyzer transcription with an automated, cloud-native Laboratory Information System. From instantaneous thermal barcode accessioning to automated bidirectional HL7/ASTM analyzer worklists, rules-based delta verification, and itemized billing claim scrubbing, LIS365 operates as your single operational source of truth.
Enterprise Core Advantages
Engineered to streamline end-to-end diagnostic velocity while ensuring 100% adherence to CLIA, CAP, and HIPAA standards.
Why Choose LIS365 for Modern Laboratory Automation?
Traditional laboratories face escalating test volumes, acute technician shortages, and razor-thin insurance reimbursements. LIS365 bridges clinical excellence and financial sustainability in a single unified laboratory information system.
Patient Management & Demographics
Centralized patient index supporting fast demographic capture, insurance eligibility validation, and medical history synchronization. Eliminates duplicate patient identities across multi-clinic reference networks.
- Real-time insurance policy verification
- Automated patient duplicate detection
- Lifetime electronic patient health record archives
Dynamic Electronic Requisitions
Customizable electronic requisition forms tailored by specialty—toxicology, molecular, infectious disease, or routine blood panels. Enforces mandatory collection times, ICD-10 diagnostic codes, and medical necessity rules.
- 1-click visit creation for collection dates
- Standardized & specialty requisition templates
- Barcode label auto-generation at accessioning
Omnichannel Result Reporting
Instantly distribute verified lab results to ordering providers in their preferred formats. Automated delivery via HL7 feeds directly into provider EHRs, encrypted email, secure provider web portals, or automated fax.
- Immediate provider result notification triggers
- Dynamic PDF and Excel export delivery
- Color-coded critical out-of-range alerts
Integrated Billing & A/R Recovery
Backed by 16+ years of specialized laboratory billing expertise. Generate itemized weekly and monthly invoices, scrub claims for accurate CPT/ICD-10 coding, and accelerate third-party insurance reimbursement.
- Drastically lower insurance claim denial rates
- Forensic billing & aged A/R recovery auditing
- Electronic Remittance Advice (ERA) automated posting
Configurable Rules & Daily QC
Configurable decision rules guide technologists throughout testing. Automate reflex testing, Westgard QC rule evaluations, and delta checks to safeguard diagnostic accuracy and achieve CLIA/CAP readiness.
- Streamlined daily Quality Control ordering
- Automated reflex testing logic on abnormal findings
- Westgard multi-rule evaluation & Levey-Jennings charts
Zero Hardware Footprint
Deploy rapidly without purchasing expensive on-premise servers, database licenses, or backup drives. LIS365 runs in Microsoft Azure with continuous high availability, automated security patching, and unlimited data retention.
- No added storage costs as volume expands
- Scalable architecture from startup labs to hospital chains
- Bank-grade encryption for all data at rest and in transit
Explore LIS365's Central Laboratory Dashboards
Click any dashboard screen below to inspect high-resolution operational walkthroughs—designed for laboratory directors, medical technologists, and administrative personnel.
Executive Analytics
1. Central Command Dashboard
High-level executive visualization of test volumes, department throughput, pending requisitions, and real-time revenue collection metrics.
Intake & Accessioning
2. Digital Requisition Management
Streamlined sample receiving at the Requisitions Menu with automated validation of required patient demographics and physician orders.
Analyzer Interfacing
3. Universal Analyzer Hub
Automated interface monitoring with fail-safe alerts for file counts, export queue pending minutes, and communication heartbeat diagnostics.
Toxicology Module
4. Toxicology & Drug Adherence
Specialized clinical matrix displaying illicit vs. prescribed drug detection, LC-MS/MS confirmation status, and comprehensive risk profiles.
Provider Portal
5. Provider Delivery Console
Physicians access instant cumulative patient trends, abnormal flag alerts, and downloadable signed diagnostic records on web or mobile.
Billing Engine
6. RCM & Invoicing Management
Automated notification alerts when weekly and monthly client invoices are finalized, complete with itemized Excel and PDF ledgers.
How LIS365 Transforms Daily Laboratory Operations
Click through each operational phase below to explore how LIS365 manages the complete specimen journey from initial clinic requisition to certified diagnostic release and insurance reimbursement.
Electronic Requisitions & Patient Demographics
Eliminate illegible paper requisitions and missing clinical data. Clinics and phlebotomists create visits directly through standard or custom web requisition forms, capturing demographics, ICD-10 medical necessity codes, and collection timestamps before the sample ever reaches the testing bench.
Orders appear immediately at lab receiving with real-time tracking numbers.
Pre-validates ICD-10 diagnosis against ordered CPT panels to eliminate claim denials.
- Electronic Signature Verification
- Insurance Card Image Upload
- Multi-Clinic Location Routing
Thermal Barcoding & Specimen Traceability
Upon specimen arrival, lab intake staff scan the accession number or generate unified 1D/2D thermal barcode labels for each primary tube and aliquot. Complete chain of custody is maintained from refrigerator placement to analyzer racks.
Generates thermal tube labels compatible with Zebra, Dymo, and network printers.
Know exactly which freezer shelf, box, and rack row holds every patient sample.
- Code 128, DataMatrix & QR Support
- High-Throughput Batch Scanning
- Automated Sample Rejection Logging
Bidirectional Interfacing with All Major Analyzers
Transform manual analyzer operations into seamless automated pipelines. LIS365 connects directly with clinical chemistry, hematology, immunoassay, toxicology, and molecular instruments via open HL7 and ASTM protocols.
LIS365 sends test orders to instruments; instruments return raw data automatically.
Monitors file queues, connection heartbeats, and notifies admins of feed drops.
- ASTM E1381 / E1394 Standard Support
- HL7 v2.3, v2.5 & v2.7 Protocols
- Direct TCP/IP & RS232 Socket Drivers
Rules-Based Decision Support & Quality Control
Protect patients and uphold laboratory accreditation standards. Rules-based engine evaluates Westgard multi-rules on daily QC controls, checks delta variance against historical records, and triggers automatic reflex testing.
Normal test results that satisfy strict criteria release automatically without delay.
Flags life-threatening abnormal results with mandatory technologist acknowledgement.
- Automated Levey-Jennings QC Graphs
- Digital Technologist Sign-Off Logging
- Unalterable Audit Trail Record Tracking
Instant Result Delivery & Clean Claim Invoicing
Close the diagnostic loop in record time. Final reports deliver automatically to physician EHRs and patient portals. Simultaneously, the billing module compiles completed test codes, scrubs claims, and generates itemized weekly/monthly invoices.
Auto-fax, HL7 ORU, secure portal, and encrypted email options.
Weekly and monthly billing registers with full CPT line item transparency.
- Electronic 837P Claim Pre-Scrubbing
- Automated Client Invoicing Notifications
- Dedicated Forensic A/R Consulting Option
Watch LIS365 in Action
See how clinical laboratories automate sample intake, orchestrate bidirectional analyzer interfaces, and issue verified diagnostic reports in minutes.
Click to Watch LIS365 Product Walkthrough
Official Video Tour • 5 Minutes
Download the Official LIS365 Solution Brochure & One-Pager
Get the complete technical overview, instrument interfacing protocol matrix, CLIA/HIPAA compliance specifications, and billing service architecture in a concise, shareable PDF.
LIS365 Solution Brief
Tailored Modules for Every Laboratory Specialty
From low-volume startups and physician practice labs (POLs) to high-volume commercial reference centers, LIS365 provides dedicated workflow configurations to meet your unique diagnostic and regulatory needs.
Toxicology & Drug Adherence
Engineered specifically for reference labs, pain management clinics, and addiction recovery centers. Correlates prescribed medications with immunoassay screening and LC-MS/MS confirmatory findings.
- Prescribed vs. non-prescribed detection matrix
- Configurable clinical cut-off concentrations
- Patient longitudinal compliance trend graphs
Chemistry, Hematology & Urinalysis
High-throughput processing of routine and esoteric clinical panels (CBC, CMP, Lipid, Thyroid). Features automatic dilution calculation, automated panic value warnings, and specimen stability alerts.
- Age- and gender-specific normal reference ranges
- Automated delta-checking against past encounters
- Multi-analyzer workload load balancing
Molecular Diagnostics & PCR
Support for 96-well plate mapping, real-time RT-PCR instrument exports, viral load quantitation, and automated respiratory, UTI, and STI syndromic pathogen panel interpretation.
- Graphical 96/384 well plate layout designer
- Automatic positive/negative control validation
- Public health CDC/State electronic reporting (ELR)
Startup Labs & Clinic Systems
Many practices wish to establish in-house testing but find traditional LIS software cost-prohibitive. LIS365 offers an entry-level package designed to automate startups with effortless scalability as volumes expand.
- Accessible subscription pricing with zero capital lock-in
- Seamless 1-week rapid onboarding and deployment
- Effortless expansion to full enterprise LIS365 tier
Provider & Phlebotomy Web Portal
Give ordering physicians, clinic nurses, and phlebotomists a secure, branded self-service portal to place test orders, print collection manifests, view real-time testing progress, and retrieve signed PDF reports.
- White-labeled portal with your laboratory branding
- Role-based permissions for physicians and staff
- Secure, mobile-responsive smartphone access
Laboratory Billing Services
Over 16 years of hands-on laboratory billing, forensic A/R recovery, and reimbursement consulting. Outsource your billing completely or leverage our automated engine to stop revenue leaks and optimize collections.
- Same-day daily charge and EOB processing
- Percentage-of-net-collections pricing structure
- No long-term contracts—proven performance every month
Measurable Operational & Financial ROI from Day 1
By eliminating fragmented legacy spreadsheets, manual instrument transcription, and delayed paper requisitions, LIS365 accelerates test throughput while protecting your bottom line.
Deploy with Complete Confidence on Microsoft Azure Cloud
LIS365 combines strict CLIA, CAP, and HIPAA adherence with resilient Microsoft Azure enterprise cloud hosting engineered by certified specialists at Guru Group LLC.
CLIA & HIPAA Audit Ready
Delivered by Guru Group LLC—delivering certified enterprise healthcare software extensions, HIPAA-grade data encryption, and 24/7 technical support.
Frequently Asked Questions About LIS365
Everything you need to know about analyzer connectivity, EHR interoperability, regulatory compliance, billing models, and migration.
Ready to Boost Diagnostic Speed & Protect Your Lab's Revenue?
Join forward-thinking clinical and toxicology laboratories across the United States that trust LIS365 to eliminate manual processing errors and deliver rapid, compliant diagnostic results.